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Garetosmab

CAT: 0804-HY-P99632-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99632-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Garetosmab (REGN 2477) is a fully human IgG4 monoclonal antibody that specifically inhibits activin A. Garetosmab can be used for fibrodysplasia ossificans progressiva (FOP) research[1].
CAS Number
2097125-54-5
Product Name Alternative
REGN 2477
UNSPSC
12352203
Target
TGF-β Receptor
Type
Inhibitory Antibodies
Related Pathways
TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/garetosmab.html
Purity
99.57
Solubility
10 mM in DMSO
Smiles
[Garetosmab]
Molecular Weight
(145.52 kDa)
References & Citations
[1]Frédéric Vanhoutte, et al. Pharmacokinetics and Pharmacodynamics of Garetosmab (Anti-Activin A) : Results From a First-in-Human Phase 1 Study. J Clin Pharmacol. 2020 Nov;60 (11) :1424-1431.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3

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