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8-Hydroxyoctanoic acid-thalidomide

CAT: 0804-HY-162611Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162611Size:1 Each
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Description
8-Hydroxyoctanoic acid-thalidomide is an E3 Ligase Ligand-Linker Conjugate. 8-Hydroxyoctanoic acid-thalidomide can be used to synthesize Lw13.
CAS Number
2399454-65-8
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8-hydroxyoctanoic-acid-thalidomide.html
Smiles
O=C(O)CCCCCCCNC1=C2C(C(N(C3CCC(NC3=O)=O)C2)=O)=CC=C1
Molecular Formula
C21H27N3O5
Molecular Weight
401.46
References & Citations
[1]Zhang X, et al. Discovery of a potent and selective JAK1-targeting PROTAC degrader with anti-tumor activities. Bioorg Med Chem Lett. 2024 Sep 1;109:129838.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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