Products for Research Use Only
RegisterLogin

(R) -Ketorolac

CAT: 0804-HY-B0580B-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0580B-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
(R) -Ketorolac is an orally active Cdc42 and Rac1 inhibitor. (R) -Ketorolac inhibits GTPase. (R) -Ketorolac alters ovarian cancer cell behaviors critical for invasion and metastasis. (R) -Ketorolac ameliorates cancer-associated cachexia[1][2][3].
CAS Number
66635-93-6
Product Name Alternative
(+) -Ketorolac
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-ketorolac.html
Purity
99.65
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1=CC=CC=C1)C2=CC=C3N2CC[C@H]3C(O)=O
Molecular Formula
C15H13NO3
Molecular Weight
255.27
Precautions
H315, H319, H335
References & Citations
[1]Handley DA, et al. Preclinical enantioselective pharmacology of (R) - and (S) - ketorolac. J Clin Pharmacol. 1998 Feb;38 (2S) :25S-35S.|[2]Guo Y, Kenney SR, Muller CY, et al. R-Ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis. Mol Cancer Ther. 2015;14 (10) :2215-2227. |[3]Chrysostomou SE, et al. R-ketorolac ameliorates cancer-associated cachexia and prolongs survival of tumour-bearing mice. J Cachexia Sarcopenia Muscle. 2024 Apr;15 (2) :562-574.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-B0580-01Ketorolac
HY-B0580DKetorolac (hydrochloride)
HY-B0580A-01(S) -Ketorolac
HY-B0580C-01Ketorolac (hemicalcium)
HY-B0580S2Ketorolac-13C6
HY-B0580R-01Ketorolac (Standard)
HY-B0580S1-01Ketorolac-d4
HY-B0580S-01Ketorolac-d5
HY-B0138-01Ketorolac (tromethamine salt)
HY-B0138R-01Ketorolac (tromethamine salt) (Standard)

Alternative Products

CatalogName
281130-01Ketorolac
CS-O-03100Ketorolac-13C6
464206-01Rac Ketorolac

Popular Products