Products for Research Use Only
RegisterLogin

Schisandrin B (Standard)

CAT: 0804-HY-N0089R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0089R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Schisandrin B (Standard) is the analytical standard of Schisandrin B. This product is intended for research and analytical applications. Schisandrin B (γ-Schisandrin) is a biphenylcyclooctadiene derivative isolated from Schisandra chinensis and has been shown to have antioxidant effects on the liver and heart of rodents.
CAS Number
61281-37-6
Product Name Alternative
γ-Schisandrin (Standard) ; Wuweizisu B (Standard)
UNSPSC
12352005
Target
Autophagy; Reactive Oxygen Species (ROS) ; Reference Standards
Type
Reference Standards
Related Pathways
Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/schisandrin-b-standard.html
Smiles
CC(C1)C(C)CC2=CC(OC)=C(OC)C(OC)=C2C3=C1C=C4OCOC4=C3OC
Molecular Formula
C23H28O6
Molecular Weight
400.46
References & Citations
[1]Checker R, et al. Schisandrin B exhibits anti-inflammatory activity through modulation of the redox-sensitive transcription factors Nrf2 and NF-κB. Free Radic Biol Med. 2012 Oct 1;53 (7) :1421-30.|[2]Lam PY, et al. Schisandrin B as a hormetic agent for preventing age-related neurodegenerative diseases. Oxid Med Cell Longev. 2012;2012:250825.|[3]Zeng KW, et al. Schisandrin B exerts anti-neuroinflammatory activity by inhibiting the Toll-like receptor 4-dependent MyD88/IKK/NF-κB signaling pathway in lipopolysaccharide-induced microglia. Eur J Pharmacol. 2012 Oct 5;692 (1-3) :29-37.|[4]Liu Z, et al. Schisandrin B attenuates cancer invasion and metastasis via inhibiting epithelial-mesenchymal transition. PLoS One. 2012;7 (7) :e40480.|[5]Zhu S, et al. Protective effect of schisandrin B against cyclosporine A-induced nephrotoxicity in vitro and in vivo. Am J Chin Med. 2012;40 (3) :551-66.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Chemical Information

Schisandrin B

Schizandrin B has been reported in Schisandra sphenanthera, Schisandra propinqua, and other organisms with data available.

CAS Number61281-37-6
PubChem CID108130
IUPAC Name3,4,5,19-tetramethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaene
Molecular FormulaC23H28O6
Molecular Weight400.5
XLogP5.1
Topological Polar Surface Area55.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count29
Formal Charge0
Complexity543
SMILES
CC1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4CC1C)OC)OC)OC)OC)OCO3
InChI
InChI=1S/C23H28O6/c1-12-7-14-9-16(24-3)20(25-4)22(26-5)18(14)19-15(8-13(12)2)10-17-21(23(19)27-6)29-11-28-17/h9-10,12-13H,7-8,11H2,1-6H3
InChIKey
RTZKSTLPRTWFEV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Schisandrin B
CAS: 61281-37-6
CID: 108130
Formula: C23H28O6
MW: 400.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight400.5
XLogP35.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass400.18858861
Monoisotopic Mass400.18858861
Topological Polar Surface Area55.4 Ų
Heavy Atom Count29
Formal Charge0
Complexity543
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-N0691RSchisandrin (Standard)
HY-N0693R-01Schisandrin A (Standard)
HY-N0089-01Schisandrin B
HY-N0690RSchisandrin C (Standard)
HY-N2267-01(+) -Schisandrin B
HY-N0691-01Schisandrin
HY-N0693-01Schisandrin A
HY-N0692R-01Schisandrol B (Standard)
HY-N0690-01Schisandrin C
HY-N9233Schisandrin C epoxide

Alternative Products

CatalogName
T2926-01Schisandrin A
SM1085-25mgSchisandrin
TN1780-01(+) -Schisandrin B
465945-01Schisandrin C
AB0496Schisandrin B
A14570-100Schisandrin A 100mg
A14570-5Schisandrin A 5mg

Popular Products