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COR627

CAT: 0804-HY-119256Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119256Size:1 Each
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Description
COR627 is a GABA receptor positive allosteric modulator with the ability to enhance GABA activity. COR627 exhibits effects on GABA and baclofen stimulation in rat cortical membranes and can increase its affinity for GABA (B) receptors. In vivo experiments have shown that COR627 can enhance the sedative/hypnotic effects of baclofen at pretreatment ineffective doses[1].
CAS Number
329221-34-3
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cor627.html
Smiles
O=C(OC)C1=C(SC(C)=C1CC)NC(C23CC4CC(CC(C3)C4)C2)=O
Molecular Formula
C20H27NO3S
Molecular Weight
361.50
References & Citations
[1]Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA (B) receptor
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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