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SRSF3 Polyclonal Antibody

CAT: 0763-E-AB-32966-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-32966-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the serine/arginine (SR) -rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene.
Abbreviation
SRSF3
UniProt
P84103
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from the C-terminal region of human
Target
Arginine/serine-rich 3, Pre mRNA splicing factor SRP20, Pre-mRNA-splicing factor SRP20, Serine/arginine-rich splicing factor 3, Splicing factor, Splicing factor arginine/serine rich 20 kD, Splicing factor arginine/serine rich 3, SRp20, SRSF3, SRSF3, X16
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Dilution
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50%glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
19kDa
Observed Molecular Weight
25kDa
Isotype
IgG

UniProtKB · P84103

Serine/arginine-rich splicing factor 3

SRSF3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P84103
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SRSF3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4E241, O08831, P23152, Q5R3K0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Biological process

mRNA processingmRNA splicingmRNA transportTransport

Domain

Repeat

Molecular function

RNA-binding

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