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Rosolic acid

CAT: 0804-HY-W104821-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W104821-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rosolic Acid is an activator of Nrf2, as well as its downstream targets. Rosolic Acid increases the levels of angiogenic factors, decreases inflammation (TNF-α and IL-1β) and apoptotic markers (CXCL10 and CCL2) . Rosolic Acid restores the function of pancreatic cells and protects endothelial cells (ECs) from endoplasmic reticulum stressed[1].
CAS Number
603-45-2
UNSPSC
12352200
Hazard Statement
H315, H319
Target
Keap1-Nrf2
Type
Biochemical Assay Reagents
Related Pathways
NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/rosolic-acid.html
Solubility
10 mM in DMSO
Smiles
C1=C(C=CC(=C1)O)C(=C2C=CC(=O)C=C2)C3=CC=C(C=C3)O
Molecular Formula
C19H14O3
Molecular Weight
290.31
Precautions
H315, H319
References & Citations
[1]Amin KN, et al. Effect of Rosolic acid on endothelial dysfunction under ER stress in pancreatic microenvironment. Free Radic Res. 2021 Jun;55 (6) :698-713.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported