Benzo[a]pyrene (Standard)

• UNSPSC Description:

  Benzo[a]pyrene (Standard) is the analytical standard of Benzo[a]pyrene. This product is intended for research and analytical applications. Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies.

• Target Antigen:

  Endogenous Metabolite

• Type:

  Reference Standards

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/benzo-a-pyrene-standard.html

• Purity:

  99.76

• Smiles:

  C12=C(C=C3)C=C(C=CC=C4)C4=C1C=CC5=CC=CC3=C25

• Molecular Weight:

  252.31

• References & Citations:

  [1]Saeko Onami, et al. Dosimetry for lung tumorigenesis induced by urethane, 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK), and benzo[a]pyrene (B[a]P) in A/JJmsSlc mice. J Toxicol Pathol. 2017 Jul; 30(3): 209–216.|[2]Yeo CD, et al. Roflumilast treatment inhibits lung carcinogenesis in benzo(a)pyrene-induced murine lung cancer model. Eur J Pharmacol. 2017 Oct 5;812:189-|[3]Foth H, et al. Pharmacokinetics of low doses of benzo [a] pyrene in the rat[J]. Food and chemical toxicology, 1988, 26(1): 45-51.|[4]Anandakumar P, et al. Capsaicin inhibits benzo(a)pyrene-induced lung carcinogenesis in an in vivo mouse model. Inflamm Res. 2012 Nov;61(11):1169-75.|[5]Kasala ER, et al. Benzo(a)pyrene induced lung cancer: Role of dietary phytochemicals in chemoprevention. Pharmacol Rep. 2015 Oct;67(5):996-1009.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• CAS Number:

  50-32-8