Products for Research Use Only
RegisterLogin

Echitamine (chloride)

CAT: 0804-HY-N3797ASize: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N3797ASize:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Echitamine (Ditaine) chloride is the major monoterpene indole alkaloid present in Alstonia scholaris with potent anti-tumour activity. Echitamine chloride induces DNA fragmentation and cells apoptosis. Echitamine chloride inhibits pancreatic lipase with an IC50 of 10.92 μM[1][2].
CAS Number
6878-36-0
Product Name Alternative
Ditaine (chloride)
UNSPSC
12352005
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/echitamine-chloride.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C([C@@]([C@@](C1=CC=CC=C1N2)(CC3)[C@]2([C@H]4O)[N+]3(C/C5=C/C)C)([C@H]5C4)CO)OC.[Cl-]
Molecular Formula
C22H29ClN2O4
Molecular Weight
420.93
References & Citations
[1]Ganesh Chandra Jagetia, et al. Evaluation of the Cytotoxic Effect of the Monoterpene Indole Alkaloid Echitamine In-Vitro and in Tumour-Bearing Mice. J Pharm Pharmacol. 2005 Sep;57 (9) :1213-9.|[2]Ginson George, et al. Development and Validation of a New HPTLC-HRMS Method for the Quantification of a Potent Pancreatic Lipase Inhibitory Lead Echitamine From Alstonia scholaris. Nat Prod Res. 2019 Dec 24;1-5.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-W012954S-01TMA chloride-d12 (chloride)
HY-N8262Dehydrocorybulbine (chloride)
HY-N0926A-01Columbamine (chloride)
HY-B0567-01Dequalinium (Chloride)
HY-W012412-01Tetrapropylammonium (chloride)
HY-W011087-01Benzyldimethyltetradecylammonium (chloride)
HY-B1793-01Tetraethylammonium (chloride)
HY-16747-01Maralixibat (chloride)
HY-126397-01MnTBAP (chloride)
HY-N0640-01Kuromanin (chloride)

Alternative Products

CatalogName
MBS5817560Echitamine chloride
TN3917Echitamine
189775-01Phenyl Methanesulphonyl Chloride (α-Toluenesulphonyl Chloride; Phenylmethylsulphonyl Chloride)
3125490Tin chloride (stannous chloride)
3121645Cobalt chloride (Cobaltous chloride)
3121825Cupric chloride (Copper chloride)
sc-279274Lithium chloride-potassium chloride
TRC-B188800-5GPhenylacetyl Chloride(Benzeneacetyl Chloride)
3125225Stannous chloride (tin chloride)
3123430Manganous chloride (Manganese chloride)

Popular Products