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S22AC rabbit pAb

CAT: 0855-ES13264-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES13264-01Size:50 µL
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Background
The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Description
The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],
UniProt
Q96S37
Swiss Prot
Q96S37
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human S22AC AA range: 18-68
Target
S22AC
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Apical cell membrane ; Multi-pass membrane protein .
Gene ID (Human)
116085

UniProtKB · Q96S37

Solute carrier family 22 member 12

S22AC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96S37
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC22A12
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B7WPG1, G3XAN7, Q19PF7, Q19PF8, Q19PF9, Q19PG0, Q6UXW3, Q96DT2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

Disease

Disease variant

PTM

GlycoproteinPhosphoprotein

Biological process

Ion transportTransport

Domain

TransmembraneTransmembrane helix

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