Norcyclizine

CAT: 0804-HY-W013376-01Size: 10 gDry Ice: NoHazardous: No

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CAT#:0804-HY-W013376-01Size:10 g

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Description

Norcyclizine is a piperazine compound that can be used for the synthesis of antimicrobial agents. 1-Benzhydrylpiperazine derivatives have been found to enhance the antibacterial activity of β-lactam antibiotics (Oxacillin, HY-B0925A) against Methicillin -resistant Staphylococcus aureus (MRSA). This enhancement is likely achieved by inhibiting the allosteric site of PBP2a. Additionally, 1-Benzhydrylpiperazine can also serve as a pharmacological scaffold for the synthesis of anticancer agents[1][2].

CAS Number

841-77-0

Product Name Alternative

1- (Diphenylmethyl) piperazine; 1-Benzhydrylpiperazine

UNSPSC

12352005

Hazard Statement

H302

Target

Antibiotic; Bacterial; Penicillin-binding protein (PBP)

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/norcyclizine.html

Purity

99.73

Smiles

C1(C(N2CCNCC2)C3=CC=CC=C3)=CC=CC=C1

Molecular Formula

C17H20N2

Molecular Weight

252.35

Precautions

H302

References & Citations

[1]Witek K, et al. Chalcogen-Varied Imidazolone Derivatives as Antibiotic Resistance Breakers in Staphylococcus aureus Strains. Antibiotics (Basel) . 2023 Nov 11;12 (11) :1618.|[2]Ananda Kumar CS et al. Synthesis and in vitro antiproliferative activity of novel 1-benzhydrylpiperazine derivatives against human cancer cell lines. Eur J Med Chem. 2009 Mar;44 (3) :1223-9.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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Catalog	Name
PDK0373	Norcyclizine

Norcyclizine

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