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Aurantio-obtusin

CAT: 0804-HY-N0261-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0261-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aurantio-obtusin is a anthraquinone compound that can be extracted from cassia seed. Aurantio-obtusin has the effects of decreasing blood pressure, decreasing blood lipids and anti-inflammatory.Aurantio-obtusin is an orally active vasodilator. Aurantio-obtusin ameliorates hepatic steatosis through AMPK/ autophagy- and AMPK/TFEB mediated inhibition of lipid accumulation[1][2][3].
CAS Number
67979-25-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX; TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/aurantio-obtusin.html
Purity
99.89
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C2=C(C=C(C)C(O)=C2OC)C(C3=CC(O)=C(OC)C(O)=C13)=O
Molecular Formula
C17H14O7
Molecular Weight
330.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Li, Shuzhen, et al. Aurantio-obtusin relaxes systemic arteries through endothelial PI3K/AKT/eNOS-dependent signaling pathway in rats. Journal of pharmacological sciences vol. 128,3 (2015) : 108-15.|[2]Hou Jingyi, et al. Anti-Inflammatory Effects of Aurantio-Obtusin from Seed of Cassia obtusifolia L. through Modulation of the NF-κB Pathway. Molecules (Basel, Switzerland) vol. 23,12 3093. 27 Nov. 2018.|[3]Zhou Fei, et al. Aurantio-Obtusin Attenuates Non-Alcoholic Fatty Liver Disease Through AMPK-Mediated Autophagy and Fatty Acid Oxidation Pathways. Frontiers in pharmacology vol. 12 826628. 11 Jan. 2022.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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