Obtusin

• Description:

  Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC50 of 11.12 μM and a Ki of 6.15 μM. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression[1].

• UNSPSC:

  12352005

• Target:

  Monoamine Oxidase

• Type:

  Natural Products

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/obtusin.html

• Purity:

  99.10

• Solubility:

  DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C1C2=C (C=C (C) C (O) =C2OC) C (C3=CC (OC) =C (OC) C (O) =C13) =O

• Molecular Formula:

  C18H16O7

• Molecular Weight:

  344.32

• References & Citations:

  Cassia obtusifolia

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  70588-05-5