BECN1 Polyclonal Antibody

CAT: 0763-AN006940L-01Size: 25 µLDry Ice: NoHazardous: No

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CAT#:0763-AN006940L-01Size:25 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

Abbreviation

BECN1

UniProt

Q14457

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant Human BECN1 protein expressed by E.coli

Target

ATG; VPS; BECN; ATG6; VPS30; beclin1; Beclin 1; BECN1; beclin-1; ATG6 Autophagy Related 6 Homolog; Coiled-Coil; Myosin-Like BCL2 Interacting Protein; GT197; ATG6; beclin1; beclin-1; VPS30; APG6; ATG 6; Bcl-2-interacting protein beclin; Beclin 1 (coiled coil moesin like BCL2 interacting protein) ; Beclin 1 autophagy related; BECN 1; Coiled coil myosin like BCL2 interacting protein; Coiled-coil myosin-like BCL2-interacting protein; Protein GT197; VPS 30

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

Field of Research

Epigenetics and Nuclear Signaling; Cancer; Microbiology; Metabolism

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000

Buffer

PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

52 kDa

Observed Molecular Weight

52 kDa

Isotype

IgG

UniProtKB · Q14457

Beclin-1

BECN1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q14457
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: BECN1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: B2R6N7, O75595, Q9UNA8

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Biological process

Antiviral defenseApoptosisAutophagyCell cycleCell divisionEndocytosisHost-virus interaction

Domain

Coiled coil

Cellular component

CytoplasmCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusMembraneMitochondrionNucleus

Product Datasheet

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