ERAP1-IN-3

• Description :

  ERAP1-IN-3 (compound 13) is a potent endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor, with a pIC50 of 8.6. ERAP1-IN-3 has potential for the research of cancer immunotherapy and autoimmune disease[1].

• UNSPSC :

  12352005

• Target :

  Aminopeptidase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/erap1-in-3.html

• Smiles :

  O=C(C1(NC(CN2C(SC3=CC=C(C4=CC=CC=C4)C=C23)=O)=O)CCCCC1)O

• Molecular Formula :

  C22H22N2O4S

• Molecular Weight :

  410.49

• References & Citations :

  [1]Hryczanek RP, et, al. Optimization of Potent and Selective Cyclohexyl Acid ERAP1 Inhibitors Using Structure- and Property-Based Drug Design. CS Med. Chem. Lett. 2024, 15, 12, 2107-2114.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported