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ERAP1-IN-1

CAT: 0804-HY-133125-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-133125-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 competitively inhibits ERAP1 activity towards a nonamer peptide representative of physiological substrates[1].
CAS Number
865273-97-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335, H413
Target
Aminopeptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/erap1-in-1.html
Purity
98.77
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC=C(OC)C(S(=O)(NC2=CC(C(F)(F)F)=CC=C2N3CCCCC3)=O)=C1
Molecular Formula
C20H21F3N2O5S
Molecular Weight
458.45
Precautions
H302, H315, H319, H335, H413
References & Citations
[1]Maben Z, et al. Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1. J Med Chem. 2019 Dec 30.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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