ERAP1-IN-1

• Description :

  ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 competitively inhibits ERAP1 activity towards a nonamer peptide representative of physiological substrates[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335, H413

• Target :

  Aminopeptidase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/erap1-in-1.html

• Purity :

  98.77

• Solubility :

  DMSO : 250 mg/mL (ultrasonic)

• Smiles :

  O=C(O)C1=CC=C(OC)C(S(=O)(NC2=CC(C(F)(F)F)=CC=C2N3CCCCC3)=O)=C1

• Molecular Formula :

  C20H21F3N2O5S

• Molecular Weight :

  458.45

• Precautions :

  H302, H315, H319, H335, H413

• References & Citations :

  [1]Maben Z, et al. Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1. J Med Chem. 2019 Dec 30.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [865273-97-8]