Borapetoside E

• Description :

  Borapetoside E can be isolated from T. crispa. Borapetoside E improves hyperglycemia, insulin resistance, hepatic steatosis, hyperlipidemia, and oxygen consumption in obese mice. Borapetoside E also inhibits SREBPs expression in the liver and adipose tissue[1].

• UNSPSC :

  12352005

• Target :

  Fatty Acid Synthase (FASN)

• Type :

  Natural Products

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/borapetoside-e.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@]12[C@](CCC=C2C(OC)=O)([H])[C@@](C)([C@@]3([H])C[C@]1([H])OC3=O)C[C@@H](C4=COC=C4)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO

• Molecular Formula :

  C27H36O11

• Molecular Weight :

  536.57

• References & Citations :

  [1]Xu Y, et al. Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice. J Nat Prod. 2017 Aug 25;80 (8) :2319-2327.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [151200-49-6]