Borapetoside E

• Description:

  Borapetoside E can be isolated from T. crispa. Borapetoside E improves hyperglycemia, insulin resistance, hepatic steatosis, hyperlipidemia, and oxygen consumption in obese mice. Borapetoside E also inhibits SREBPs expression in the liver and adipose tissue[1].

• UNSPSC:

  12352005

• Target:

  Fatty Acid Synthase (FASN)

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/borapetoside-e.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@]12[C@] (CCC=C2C (OC) =O) ([H]) [C@@] (C) ([C@@]3 ([H]) C[C@]1 ([H]) OC3=O) C[C@@H] (C4=COC=C4) O[C@@H]5O[C@@H] ([C@H] ([C@@H] ([C@H]5O) O) O) CO

• Molecular Formula:

  C27H36O11

• Molecular Weight:

  536.57

• References & Citations:

  [1]Xu Y, et al. Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice. J Nat Prod. 2017 Aug 25;80 (8) :2319-2327.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  151200-49-6