Borapetoside E

• UNSPSC Description:

  Borapetoside E can be isolated from T. crispa. Borapetoside E improves hyperglycemia, insulin resistance, hepatic steatosis, hyperlipidemia, and oxygen consumption in obese mice. Borapetoside E also inhibits SREBPs expression in the liver and adipose tissue[1].

• Target Antigen:

  Fatty Acid Synthase (FASN)

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/borapetoside-e.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@]12[C@](CCC=C2C(OC)=O)([H])[C@@](C)([C@@]3([H])C[C@]1([H])OC3=O)C[C@@H](C4=COC=C4)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO

• Molecular Weight:

  536.57

• References & Citations:

  [1]Xu Y, et al. Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice. J Nat Prod. 2017 Aug 25;80(8):2319-2327.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  151200-49-6