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Buspirone

CAT: 0804-HY-B1115A-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1115A-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Buspirone is an orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. Buspirone is an anxiolytic agent, and can be used for the generalized anxiety disorder research[1].
CAS Number
36505-84-7
UNSPSC
12352005
Hazard Statement
H301
Target
5-HT Receptor; Dopamine Receptor; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/buspirone.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N(CCCCN1CCN(C2=NC=CC=N2)CC1)C(C3)=O)CC43CCCC4
Molecular Formula
C21H31N5O2
Molecular Weight
385.50
Precautions
H301
References & Citations
[1]Salimi A, et, al. Analysis of Toxicity Effects of Buspirone, Cetirizine and Olanzapine on Human Blood Lymphocytes: in Vitro Model. Curr Clin Pharmacol. 2018;13 (2) :120-127.|[2]Kim JK, et, al. Buspirone alleviates anxiety, depression, and colitis; and modulates gut microbiota in mice. Sci Rep. 2021 Mar 17;11 (1) :6094.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
5-HT1 Receptor; D2 Receptor; mLAG-3
Citation 01
Clin Pharmacol Ther. 2025 Jul 14.|Mol Pharmacol. 2023 Nov;104 (5) :230-238.

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