FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2

CAT:

804-HY-150408-03

Size:

25 mg

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CAS Number: 2241669-84-9
UNSPSC Description: FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a linker of AUTAC4. AUTAC4 contains an p-fluorobenzylguanine (FBnG) and a phenylindole moiety, which can induce K63-linked polyubiquitination and degradation of mitochondria in HeLa cells[1].
Target Antigen: AUTACs
Type: Reference compound
Related Pathways: Autophagy;PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/fbng-cys-acetamide-ch2-peg3-ch2-ch2-ch2-nh2.html
Solubility: DMSO : 50 mg/mL (ultrasonic)
Smiles: NCCCOCCOCCOCCCNC([C@H](CSC1=NC2=C(N=C(N)NC2=O)N1CC3=CC=C(F)C=C3)NC(C)=O)=O
Molecular Weight: 622.71
References & Citations: [1]Takahashi D, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76(5):797-810.e10.
Shipping Conditions: Room Temperature
Clinical Information: No Development Reported

Cat	Name
HY-150408-03	FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2
HY-150408-04	FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2
HY-150408-02	FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2
HY-150408-01	FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2
HY-150408-05	FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2
HY-130770	Ald-CH2-PEG3-CH2-Boc
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HY-400676	NH2-PEG4-GGFG-CH2-O-CH2-Cbz
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HY-145177-03	Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc

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