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Cortodoxone (Standard)

CAT: 0804-HY-77839R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-77839R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cortodoxone (Standard) is the analytical standard of Cortodoxone. This product is intended for research and analytical applications. Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation[1][2].
CAS Number
152-58-9
Product Name Alternative
11-Deoxycortisol (Standard) ; cortexolone (Standard) ; Reichstein's substance S (Standard)
UNSPSC
12352211
Hazard Statement
H410
Target
Endogenous Metabolite; Glucocorticoid Receptor; Reference Standards
Type
Reference Standards
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/cortodoxone-standard.html
Purity
98.28
Smiles
O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(CO)=O)=C1
Molecular Formula
C21H30O4
Molecular Weight
346.46
Precautions
H410
References & Citations
[1]Gjerde H, et al. 11-Deoxycortisol induces hepatic tryptophan oxygenase in rats. Acta Pharmacol Toxicol (Copenh) . 1985 Jul;57 (1) :36-9. |[2]Peng C, et al. 11-deoxycortisol positively correlates with T cell immune traits in physiological conditions. EBioMedicine. 2024 Jan;99:104935.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

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