Iso-OMPA
CAT:
804-HY-131922-02
Size:
10 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Iso-OMPA
- Product Name Alternative: Tetraisopropyl pyrophosphoramide
- CAS Number: 513-00-8
- UNSPSC Description: Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective inhibitor of the irreversible butyrylcholinesterase (BuChE). Iso-OMPA enhances soman toxicity in rats associated with the inhibition of plasma carboxylesterase (CarbE)[1][2][3].
- Target Antigen: Cholinesterase (ChE)
- Type: Reference compound
- Related Pathways: Neuronal Signaling
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/iso-ompa.html
- Purity: 99.90
- Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : 10 mg/mL (ultrasonic)
- Smiles: O=P(NC(C)C)(NC(C)C)OP(NC(C)C)(NC(C)C)=O
- Molecular Weight: 342.36
- References & Citations: [1]Rodríguez-Fuentes G, et al. Characterization of cholinesterase activity from different tissues of Nile tilapia (Oreochromis niloticus). Mar Environ Res. 2004 Aug-Dec;58(2-5):505-9.|[2]Z Grubic, et al. Iso-OMPA-induced potentiation of soman toxicity in rat correlates with the inhibition of plasma carboxylesterases. Arch Toxicol. 1988;62(5):398-9.|[3]X Norel, et al. Degradation of acetylcholine in human airways: role of butyrylcholinesterase. Br J Pharmacol. 1993 Apr;108(4):914-9.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported