PEG2000-C-DMG
CAT:
804-HY-145411-03
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PEG2000-C-DMG
- UNSPSC Description: PEG2000-C-DMG, a pegylated lipid, can be used for the preparation of Onpattro. Onpattro, a hepatically directed investigational RNAi therapeutic agent, harnesses this process to reduce the production of mutant and wild-type transthyretin by targeting the 3′ untranslated region of transthyretin mRNA[1][2].
- Target Antigen: Liposome
- Type: Oligonucleotides
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-sugar/lipid metabolism
- Field of Research: Endocrinology
- Assay Protocol: https://www.medchemexpress.com/peg2000-c-dmg.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: CCCCCCCCCCCCCC(O[C@@H](COC(NCCCOCCOC)=O)COC(CCCCCCCCCCCCC)=O)=O.[45]
- Molecular Weight: 2610.29
- References & Citations: [1]Garber K. Alnylam launches era of RNAi drugs. Nat Biotechnol. 2018;36(9):777-778. |[2]Adams D, Gonzalez-Duarte A, O'Riordan WD, et al. Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis. N Engl J Med. 2018;379(1):11-21.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported