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STX16 rabbit pAb

CAT: 0855-ES12892-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES12892-01Size:50 µL
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Background
This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants have been found for this gene. Read-through transcription also exists between this gene and the neighboring downstream aminopeptidase-like 1 (NPEPL1) gene. [provided by RefSeq, Mar 2011]
Description
This gene encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants have been found for this gene. Read-through transcription also exists between this gene and the neighboring downstream aminopeptidase-like 1 (NPEPL1) gene. [provided by RefSeq, Mar 2011],
UniProt
O14662
Swiss Prot
O14662
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human STX16 AA range: 209-259
Target
STX16
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Golgi apparatus membrane; Single-pass type IV membrane protein.; [Isoform C]: Cytoplasm.
Gene ID (Human)
8675

UniProtKB · O14662

Syntaxin-16

STX16_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14662
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
STX16
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Syn16
EC number
—
Processing
—
Secondary accessions
A6NK32, A6NN69, A8MPP0, B7ZBN1, B7ZBN2, B7ZBN3, E1P5M0, E1P607, O14661, O14663, O60517, Q5W084, Q5W086, Q5W087, Q5XKI6, Q6GMS8, Q9H0Z0, Q9H1T7, Q9H1T8, Q9UIX5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Domain

Coiled coilTransmembraneTransmembrane helix

Cellular component

CytoplasmGolgi apparatusMembrane

PTM

Phosphoprotein

Biological process

Protein transportTransport

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