OADS

• Description :

  OADS is a Chloride channel antiporter (ClC-ec1) inhibitor (IC50: 29 μM) . OADS specifically inhibits the ClC-ec1 antiporter but not the ClC-1 channel. OADS can be used for research of osteoporosis and neurodegenerative and cardiovascular diseases[1].

• CAS Number :

  [5970-15-0]

• UNSPSC :

  12352005

• Target :

  Chloride Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Field of Research :

  Neurological Disease; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/oads.html

• Purity :

  98.25

• Smiles :

  O=S(C1=CC(NC(CCCCCCC)=O)=CC=C1/C=C/C2=CC=C(NC(CCCCCCC)=O)C=C2S(=O)(O)=O)(O)=O

• Molecular Formula :

  C30H42N2O8S2

• Molecular Weight :

  622.79

• References & Citations :

  [1]Howery AE, et al. A designed inhibitor of a CLC antiporter blocks function through a unique binding mode. Chem Biol. 2012 Nov 21;19 (11) :1460-70.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 4