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Vulpinic acid

CAT: 0804-HY-125919-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-125919-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vulpinic acid, a lichen metabolite, decreases H2O2-induced ROS production, oxidative stress and oxidative stress-related damages in human umbilical vein endothelial cells (HUVEC) . Vulpinic acid is active against staphylococci, enterococci, and anaerobic bacteria.Vulpinic acid has the potential for atherosclerosis research[1][2].
CAS Number
521-52-8
UNSPSC
12352005
Hazard Statement
H302
Target
Bacterial; Endogenous Metabolite; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/vulpinic-acid.html
Purity
99.62
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
COC(/C(C1=CC=CC=C1)=C2C(O)=C(C3=CC=CC=C3)C(O\2)=O)=O
Molecular Formula
C19H14O5
Molecular Weight
322.31
Precautions
P264-P270-P330-P501
References & Citations
[1]E Sahin, et al. Vulpinic acid, a lichen metabolite, emerges as a potential drug candidate in the therapy of oxidative stress-related diseases, such as atherosclerosis. Hum Exp Toxicol. 2019 Jun;38 (6) :675-684.|[2]M Lauterwein, et al. In vitro activities of the lichen secondary metabolites vulpinic acid, (+) -usnic acid, and (-) -usnic acid against aerobic and anaerobic microorganisms. Antimicrob Agents Chemother. 1995 Nov;39 (11) :2541-3.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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