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D-Threonine

CAT: 0804-HY-W012874-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W012874-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
D-Threonine (H-D-Thr-OH) is one of the important unnatural amino acids used as chiral building blocks in pharmaceutical drugs. D-Threonine is a metabolite of Saccharomyces cerevisiae. D-Threonine is cleaved into glycine and acetaldehyde by the catalytic action of D-threonine aldolase[1][2][3].
CAS Number
632-20-2
Product Name Alternative
H-D-Thr-OH
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Drug Intermediate; Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/d-threonine.html
Purity
98.0
Solubility
DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)
Smiles
OC([C@@H]([C@@H](O)C)N)=O
Molecular Formula
C4H9NO3
Molecular Weight
119.12
Precautions
H302, H315, H319, H335
References & Citations
[1]Ito T, et al. Enzymatic assay of D-serine using D-serine dehydratase from Saccharomyces cerevisiae. Anal Biochem. 2007 Dec 15;371 (2) :167-72. |[2]Kataoka M, et al. Isolation and characterization of D-threonine aldolase, a pyridoxal-5'-phosphate-dependent enzyme from Arthrobacter sp. DK-38. Eur J Biochem. 1997 Sep 1;248 (2) :385-93. |[3]Han SW, Shin JS. Preparation of D-threonine by biocatalytic kinetic resolution. Journal of Molecular Catalysis B: Enzymatic. 2015 Dec 1;122:227-32.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

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C6832-1000D-Threonine
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TRC-A548540-5GD-allo-Threonine
FM0465-01FMOC-D-Threonine

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