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Berkeleyacetal C

CAT: 0804-HY-N10175Size: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-N10175Size:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
959772-67-9
UNSPSC Description
Berkeleyacetal C, a meroterpenoid compound, shows favorable activity of inhibiting nitrogen oxide (NO) production of macrophages stimulated by lipopolysaccharide (LPS). Berkeleyacetal C exerts anti-inflammatory effects via inhibiting NF-κB, ERK1/2 and IRF3 signaling pathways[1].
Target Antigen
Endogenous Metabolite; Fungal
Type
Natural Products
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/berkeleyacetal-c.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](C[C@@]3([C@]4([H])[C@@]2([H])C([C@@H](O[C@]4([H])OC3=O)C)=O)C)([H])[C@]5(CO5)C(C(C(C)(O6)C)=CC1=O)=CC6=O
Molecular Weight
442.46
References & Citations
[1]Márquez-Cadena MA, et al. Synthetic Studies toward the Berkeleyacetal Core Architecture. Org Lett. 2021 Nov 15. |[2]Li SS, et al. Berkeleyacetal C, a meroterpenoid isolated from the fungus Penicillium purpurogenum MHZ 111, exerts anti-inflammatory effects via inhibiting NF-κB, ERK1/2 and IRF3 signaling pathways. Eur J Pharmacol. 2017;814:283-293.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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