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MCL0020

CAT: 0804-HY-107627-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-107627-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MCL0020 is a potent and selective melanocortin MC4 receptor antagonist, with an IC50 of 11.63 nM. MCL0020 dose-dependently and significantly attenuates restraint stress-induced anorexia without affecting food intake[1].
CAS Number
475498-26-1
UNSPSC
12352209
Hazard Statement
H302, H315, H319
Target
Melanocortin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mcl0020.html
Purity
99.93
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
NC([C@H](CC1=CC2=C(C=CC=C2)C=C1)NC([C@H](CCCNC(N)=N)NC([C@H](NC(C)=O)CC3=CC4=C(C=CC=C4)C=C3)=O)=O)=O
Molecular Formula
C34H39N7O4
Molecular Weight
609.72
Precautions
H302, H315, H319
References & Citations
[1]Chaki S, et al. Involvement of the melanocortin MC4 receptor in stress-related behavior in rodents. Eur J Pharmacol. 2003;474 (1) :95-101.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
MC4R

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