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CycloScreen Cyclodextrins Kit

CAT: 0952-K1010005Size: 1 KitDry Ice: NoHazardous: No
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CAT#:0952-K1010005Size:1 Kit
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Description
CycloScreen Cyclodextrins Kit_x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_ _x000D_
Catalog number:K1010005
Lot number:Batch Dependent
Expiration date:Batch Dependent
Package Content5 x 2 mL
Content_x000D_
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  • Œ±-cyclodextrin (5%, 2 mL)
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  • (2-hydroxypropyl)-Œ±-cyclodextrin (10%, 2 mL)
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  • methyl-Œ≤-cyclodextrin (10%, 2 mL)
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  • (2-hydroxyprop yl)-Œ≤-cyclodextrin (10%, 2 mL)
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  • (2-hydroxypropyl)-Œ≥-cyclodextrin (10%, 2 mL)
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Supplied as:CycloScreen: Cyclodextrins Kit
Keywords:α-cyclodextrin, (2-hydroxypropyl)-α-cyclodextrin, methyl-β-cyclodextrin, (2-hydroxypropyl)-β-cyclodextrins, (2-hydroxypropyl)-γ-cyclodextrins, cyclodextrin screening kit
Storage:2-8°C (short term), -20°C (long term). Avoid repeated freeze-thaw.
_x000D_  _x000D_ _x000D_ Applications_x000D_ _x000D_ CycloScreen's cyclodextrins have been proven to be effective in several applications that include:_x000D_
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  • protein refolding and stabilization
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  • small chemicals and reagents stabilization
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  • quenching of certain detergents
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  • extension of reagent shelf-life
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  • specific binding of interfering substances
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  • transport of chemical compounds
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_x000D_ With all three types of cyclodextrins included (α, β and γ as ranked by increasing molecular diameter), the kit offers the option to quickly screen for the most suitable cyclodextrin to a given application. Provided as highly concentrated solutions (5% and 10%), these cyclodextrins can be easily diluted to working concentrations. Working concentrations depend on the application, but typically range from 0.01% to 0.5%. Individual cyclodextrin solutions are available individually and in custom bulk amounts._x000D_ _x000D_ References_x000D_
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    • Cyclodextrins in drug carrier systems. Uekama K, Otagiri M. Crit Rev Ther Drug Carrier Syst. 1987;3(1):1-40.
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    • Neutron diffraction of alpha, beta and gamma cyclodextrins: hydrogen bonding patterns. Hingerty B, Klar B, Hardgrove GL, Betzel C, Saenger W. J Biomol Struct Dyn. 1984 Aug;2(1):249-60.
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      Inclusion compounds of cyclodextrins. Cramer F, Hettler H. Naturwissenschaften. 1967;54(24):625-32.

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      Analytical applications of enhanced drug luminescence. Baeyens WR, Ling BL. J Pharm Biomed Anal. 1989;7(12):1385-94.

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    • Ma Z, Wang N, He H, Tang X. Pharmaceutical strategies of improving oral systemic bioavailability of curcumin for clinical application. J Control Release. 2019 Dec 28;316:359-380.
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Short Description
Catalog #: K1010005 (1 kit)
Weight
2
Length
2.5
Width
2
Height
1.2