(2-Hydroxypropyl) -β-cyclodextrin (Highly Pure)

• Description:

  (2-Hydroxypropyl)-β-cyclodextrin (Highly Pure)_x000D_ Catalog number: B2010636_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 1 g_x000D_ Molecular Weight or Concentration: 1396 Da_x000D_ Supplied as: Powder_x000D_ Applications: versatile molecular tools in solubility studies_x000D_ Storage: RT_x000D_ Keywords: HP-β-CD_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Lu H, Sun J, Liang W, Chang Z, Rom O, Zhao Y, Zhao G, Xiong W, Wang H, Zhu T,_x000D_ Guo Y, Chang L, Garcia-Barrio MT, Zhang J, Chen YE, Fan Y. Cyclodextrin Prevents_x000D_ Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell_x000D_ Transcription Factor EB. Circulation. 2020 Aug 4;142(5):483-498. ._x000D_ _x000D_ 2: Stappaerts J, Berben P, Cevik I, Augustijns P. The effect of 2-hydroxypropyl-_x000D_ β-cyclodextrin on the intestinal permeation through mucus. Eur J Pharm Sci. 2018_x000D_ Mar 1;114:238-244._x000D_ _x000D_ 3: Conceição J, Adeoye O, Cabral-Marques HM, Sousa Lobo JM. Hydroxypropyl-β-_x000D_ Cyclodextrin and β-Cyclodextrin as Tablet Fillers for Direct Compression. AAPS_x000D_ PharmSciTech. 2018 Aug;19(6):2710-2718._x000D_ _x000D_ 4: Cheng Q, Liu G, Zhang P, Xu W, Tang K. Lipase-catalyzed hydrolysis of_x000D_ (R,S)-2,3-diphenylpropionic methyl ester enhanced by hydroxypropyl-β-_x000D_ cyclodextrin. Biotechnol Prog. 2018 Nov;34(6):1355-1362. d_x000D_ _x000D_ 5: Pons-Faudoa FP, Sizovs A, Di Trani N, Paez-Mayorga J, Bruno G, Rhudy J,_x000D_ Manohar M, Gwenden K, Martini C, Chua CYX, Varchi G, Marzinke MA, Grattoni A._x000D_ 2-Hydroxypropyl-β-cyclodextrin-enhanced pharmacokinetics of cabotegravir from a_x000D_ nanofluidic implant for HIV pre-exposure prophylaxis. J Control Release. 2019_x000D_ Jul 28;306:89-96._x000D_ _x000D_ 6: Ding Y, Pang Y, Vara Prasad CVNS, Wang B. Formation of inclusion complex of_x000D_ enrofloxacin with 2-hydroxypropyl-β-cyclodextrin. Drug Deliv. 2020_x000D_ Dec;27(1):334-343._x000D_ _x000D_ 7: Gaspar J, Mathieu J, Alvarez P. 2-Hydroxypropyl-beta-cyclodextrin (HPβCD)_x000D_ reduces age-related lipofuscin accumulation through a cholesterol-associated_x000D_ pathway. Sci Rep. 2017 May 19;7(1):2197._x000D_ _x000D_ 8: Sun H, Zong H, Wu G. 2‑Hydroxypropyl‑β‑cyclodextrin blocks autophagy flux and_x000D_ triggers caspase‑8‑mediated apoptotic cascades in HepG2 cells. Mol Med Rep. 2020_x000D_ Sep;22(3):1901-1909._x000D_ _x000D_ 9: Leonis G, Christodoulou E, Ntountaniotis D, Chatziathanasiadou MV,_x000D_ Mavromoustakos T, Naziris N, Chountoulesi M, Demetzos C, Valsami G, Damalas DE,_x000D_ Tzakos AG, Thomaidis NS, Karageorgos V, Liapakis G. Antihypertensive activity_x000D_ and molecular interactions of irbesartan in complex with 2-hydroxypropyl-β-_x000D_ cyclodextrin. Chem Biol Drug Des. 2020 Jul;96(1):668-683._x000D_ 0: El-Darzi N, Mast N, Petrov AM, Pikuleva IA. 2-Hydroxypropyl-β-cyclodextrin_x000D_ reduces retinal cholesterol in wild-type and Cyp27a1^-/-_x000D_ Cyp46a1^-/- mice with deficiency in the oxysterol production. Br J_x000D_ Pharmacol. 2021 Aug;178(16):3220-3234. _x000D_ _x000D_ Products Related to (2-Hydroxypropyl)-β-cyclodextrin (Highly Pure): Chemicals

• Short Description:

  Catalog Number: B2010636 (1 g)

• Weight:

  0.8

• Length:

  2

• Width:

  0.9

• Height:

  0.9

• Height :

  0.9