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Oxaloacetic acid

CAT: 0804-HY-W010382-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W010382-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function[1][2][3].
CAS Number
328-42-7
Product Name Alternative
2-Oxosuccinic acid
UNSPSC
12352211
Hazard Statement
H319, H402
Target
Endogenous Metabolite; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-oxosuccinic-acid.html
Purity
99.88
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(O)C(CC(O)=O)=O
Molecular Formula
C4H4O5
Molecular Weight
132.07
Precautions
H319, H402
References & Citations
[1]F. L. Breusch. The fate of oxaloacetic acid in different organs. Biochem J. 1939 Nov; 33 (11) : 1757-1770.|[2]Brian D Fink, et al. Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II-driven respiration. J Biol Chem. 2018 Dec 21;293 (51) :19932-19941.|[3]Li W, et al. Oxaloacetate acid ameliorates paraquat-induced acute lung injury by alleviating oxidative stress and mitochondrial dysfunction. Front Pharmacol. 2022 Oct 13;13:1029775.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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