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(S) -Malic acid (Standard)

CAT: 0804-HY-Y1069R-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-Y1069R-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(S) -Malic acid (Standard) is the analytical standard of (S) -Malic acid. This product is intended for research and analytical applications. (S) -Malic acid ((S) -2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive. In Vitro: It is showed that ME is essential for (S) -2-Hydroxysuccinic acid (L-malic acid) utilization in L. casei. Furthermore, deletion of either the gene encoding the histidine kinase or the response regulator of the TC system resulted in the loss of the ability to grow on (S) -2-Hydroxysuccinic acid, thus indicating that the cognate TC system regulates and is essential for the expression of ME. Transcriptional analyses shows that expression of maeE is induced in the presence of (S) -2-Hydroxysuccinic acid and repressed by glucose, whereas TC system expression is induced by (S) -2-Hydroxysuccinic acid and is not repressed by glucose[1].
CAS Number
97-67-6
Product Name Alternative
(S) -Hydroxybutanedioic acid (Standard) ; (S) -E 296 (Standard) ; L-Malic acid (Standard)
UNSPSC
12352211
Hazard Statement
H315-H319
Target
Endogenous Metabolite; Reference Standards
Type
Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/s-malic-acid-standard.html
Purity
99.62
Smiles
O=C(O)[C@@H](O)CC(O)=O
Molecular Formula
C4H6O5
Molecular Weight
134.09
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
[1]Landete JM, et al. Requirement of the Lactobacillus casei MaeKR two-component system for L-malic acid utilization via a malic enzyme pathway. Appl Environ Microbiol. 2010 Jan;76 (1) :84-95.
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards