5'-N-Ethylcarboxamidoadenosine
CAT:
804-HY-103173-04
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
5'-N-Ethylcarboxamidoadenosine
- CAS Number: 35920-39-9
- UNSPSC Description: 5'-N-Ethylcarboxamidoadenosine (NECA) is a nonselective adenosine receptor agonist.
- Target Antigen: Adenosine Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein
- Applications: Cancer-programmed cell death
- Field of Research: Cancer; Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/NECA.html
- Purity: 99.86
- Solubility: DMSO : 62.5 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O[C@H]1[C@H](N2C=NC3=C(N)N=CN=C23)O[C@H](C(NCC)=O)[C@H]1O
- Molecular Weight: 308.29
- References & Citations: [1]Knapp CM, et al. Adenosine agonists CGS 21680 and NECA inhibit the initiation of cocaine self-administration. Pharmacol Biochem Behav. 2001 Apr;68(4):797-803.|[2]Elsherbiny NM, et al. Reno-protective effect of NECA in diabetic nephropathy: implication of IL-18 and ICAM-1. Eur Cytokine Netw. 2012 Jul-Sep;23(3):78-86.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported