Adenosine-d2

Adenosine-d2

• CAS Number: 82741-17-1
• UNSPSC Description: Adenosine-d2 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio
• Target Antigen: Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog
• Type: Isotope-Labeled Compounds
• Related Pathways: Apoptosis;Autophagy;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Others
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Cancer; Metabolic Disease
• Purity: 99.92
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: NC1=C2C(N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)C([2H])([2H])O)O)O)=NC=N1
• Molecular Weight: 269.25
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Borea PA, Gessi S, Merighi S, Vincenzi F, Varani K. Pharmacology of Adenosine Receptors: The State of the Art. Physiol Rev. 2018;98(3):1591-1625.;Fredholm BB. Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported