Mal-PEG2-Val-Cit-PABA

CAT: 0804-HY-145489-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-145489-01Size:5 mg
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Description
Mal-PEG2-Val-Cit-PABA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
CAS Number
[1662687-83-3]
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-peg2-val-cit-paba.html
Purity
98.91
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCCOCCN2C(C=CC2=O)=O)=O)=O)=O
Molecular Formula
C27H38N6O9
Molecular Weight
590.63
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16 (5) :315-337.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Protease Cleavable Linker

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