Pexiganan (acetate)

• UNSPSC Description:

  Pexiganan acetate (MSI 78) is the acetate salt form of Pexiganan (HY-105088). Pexiganan acetate is an orally active broad-spectrum antimicrobial peptide, which inhibits 99% gram-positive and Gram-negative aerobic bacteria through disruption of cell membrane/cells permeability. Pexiganan acetate can be used in the research of infections, such as diabetic foot ulcer infections[1].

• Target Antigen:

  Bacterial

• Type:

  Peptides

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/pexiganan-acetate.html

• Smiles:

  CC(O)=O.NCCCC[C@@H](C(N)=O)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@H](CC1=CC=CC=C1)NC([C@H](C)NC([C@H](CCCCN)NC(CNC([C@H](CC2=CC=CC=C2)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CCCCN)NC(CNC([C@H]([C@@H](C)CC)NC(CN)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.[x]

• Molecular Weight:

  2477.17 (free base)

• References & Citations:

  [1]Lamb HM, et al. Pexiganan acetate. Drugs. 1998 Dec;56(6):1047-52; discussion 1053-4.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 3

• CAS Number:

  172820-23-4