Mannose Receptor (CD206) Recombinant Rabbit Monoclonal Antibody [PSH07-76]

Mannose Receptor (CD206) Recombinant Rabbit Monoclonal Antibody [PSH07-76]

• Description: The mannose receptor (Cluster of Differentiation 206, CD206) is a C-type lectin primarily present on the surface of macrophages, immature dendritic cells and liver sinusoidal endothelial cells, but is also expressed on the surface of skin cells such as human dermal fibroblasts and keratinocytes. It is the first member of a family of endocytic receptors that includes Endo180 (CD280), M-type PLA2R, and DEC-205 (CD205). The receptor recognises terminal mannose, N-acetylglucosamine and fucose residues on glycans attached to proteins found on the surface of some microorganisms, playing a role in both the innate and adaptive immune systems. Additional functions include clearance of glycoproteins from circulation, including sulphated glycoprotein hormones and glycoproteins released in response to pathological events. The mannose receptor recycles continuously between the plasma membrane and endosomal compartments in a clathrin-dependent manner.
• Product Name Alternative: bA541I19.1 antibody C type lectin domain family 13 member D antibody C-type lectin domain family 13 member D antibody CD 206 antibody CD206 antibody CD206 antigen antibody CLEC13D antibody CLEC13DL antibody Macrophage mannose receptor 1 antibody Macrophage mannose receptor 1 like protein 1 antibody Macrophage mannose receptor antibody Mannose receptor C type 1 antibody Mannose receptor C type 1 like 1 antibody MMR antibody MRC 1 antibody MRC1 antibody MRC1_HUMAN antibody MRC1L1 antibody OTTHUMP00000045206 antibody
• Abbreviation: Mrc1
• CAS Number: 9000-83-3
• Swiss Prot: Q61830 Mouse,
• Cellular Locus: Endosome membrane, Cell membrane.
• Host: Rabbit
• Species Reactivity: Mouse, Rat
• Immunogen: Recombinant protein within mouse Mannose Receptor (CD206) aa 1-1,409.
• Isotype: IgG
• Clone: PSH07-76
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IF-Tissue, IHC-Fr, IF-Cell, IP
• Positive Control: RAW264.7 treated with 20ng/mL mIL-4 and 10ng/mL mIL-13 for 24 hours cell lysate, Mouse lung tissue lysate, Mouse spleen tissue lysate, Rat brain tissue lysate, Rat lung tissue lysate, Rat liver tissue lysate, mouse spleen tissue, mouse liver tissue, rat liver tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:2,000 ;IHC-P: 1:1,000 ;IF-Tissue: 1:500 ;IHC-Fr: 1:500 ;IF-Cell: 1:50 ;IP: 1-2μg/sample
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 165 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes