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BRCA1 Antibody

CAT: 0013-GTR17932816-02Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR17932816-02Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This BRCA1 Antibody is an unconjugated polyclonal product. It tagets BRCA1 using a synthesized peptide derived from Human BRCA1 around the non-phosphorylation site of S1524 as the immunogen. This antibody is suitable for ELISA, IHC, WB. Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen..
Product Name Alternative
Anti-BRCA1 antibody, anti-RNF53 antibody, anti-Breast cancer type 1 susceptibility protein antibody, anti-RING finger protein 53 antibody
UniProt
P38398
Reactivity
Human
Immunogen
Synthesized peptide derived from Human BRCA1 around the non-phosphorylation site of S1524.
Target
BRCA1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution
WB: 1:500-1:2000, IHC-P: 1:100-1:300, ELISA: 1:20000
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, IHC, WB
Host or Source
Rabbit
Preservative
Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide.
Isotype
IgG

UniProtKB · P38398

Breast cancer type 1 susceptibility protein

BRCA1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P38398
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BRCA1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.27
Processing
—
Secondary accessions
E9PFZ0, O15129, Q1RMC1, Q3LRJ0, Q3LRJ6, Q6IN79, Q7KYU9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-bindingTransferase

Coding sequence diversity

Alternative initiationAlternative splicing

Biological process

Cell cycleDNA damageDNA recombinationDNA repairTranscriptionTranscription regulationUbl conjugation pathway

Cellular component

ChromosomeCytoplasmNucleus

Disease

Disease variantFanconi anemiaTumor suppressor

Ligand

Metal-bindingZinc

Domain

RepeatZinc-finger

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