D-Galactose

• UNSPSC Description:

  D-Galactose is a natural aldohexose and C-4 epimer of glucose.

• Target Antigen:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/D-Galactose.html

• Purity:

  98.0

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)|H2O : 62.5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C[C@@H]([C@H]([C@H]([C@@H](CO)O)O)O)O

• Molecular Weight:

  180.16

• References & Citations:

  [1]Csiszovszki Z, et al. Structure and function of the D-galactose network in enterobacteria. MBio. 2011 Jun 28;2(4):e00053-11.|[2]Cui X, et al. Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidativedamage in mice: protective effects of R-alpha-lipoic acid. J Neurosci Res. 2006 Aug 15;84(3):647-54.|[3]Budni J, et al. Oral administration of d-galactose induces cognitive impairments and oxidative damage in rats. Behav Brain Res. 2016 Apr 1;302:35-43.|[4]Haifeng Wei, et al. Behavioural study of the Haifeng Wei, et al. Behavioural study of the D-galactose induced aging model in C57BL/6J mice. Behav Brain Res. 2005, 157, 22.|[5]Saida Haider, et al. A high dose of short term exogenous D-galactose administration in young male rats produces symptoms simulating the natural aging process. Life Sci. 2015.|[6]Wenjing Feng, et al. Alginate Oligosaccharide Prevents against D-galactose-mediated Cataract in C57BL/6J Mice via Regulating Oxidative Stress and Antioxidant System. Curr Eye Res. 2021, 46, 6.|[7]Lei Zhong, et al. Characterization of an i.p. D-galactose-induced cataract model in rats. J Pharmacol Toxicol Methods. 2021.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  Phase 2

• CAS Number:

  59-23-4