AKR1C3-IN-1

AKR1C3-IN-1

• CAS Number: 327092-81-9
• UNSPSC Description: AKR1C3-IN-1 is a potent, highly selective inhibitor of AKR1C3, with an IC50 of 13 nM.
• Target Antigen: 17β-HSD
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/AKR1C3-IN-1.html
• Purity: 98.23
• Solubility: DMSO : ≥ 100 mg/mL
• Smiles: O=S(N1CC2=CC=CC=C2CC1)(C3=CC(C(O)=O)=CC=C3)=O
• Molecular Weight: 317.36
• References & Citations: [1]Jamieson SM, et al. 3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: highly potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3. J Med Chem. 2012 Sep 13;55(17):7746-58.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported