O-Propargyl-Puromycin

O-Propargyl-Puromycin

• CAS Number: 1416561-90-4
• UNSPSC Description: O-Propargyl-Puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-Propargyl-Puromycin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: Biochemical Assay Reagents
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/O-Propargyl-Puromycin.html
• Solubility: DMSO : ≥ 31 mg/mL|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: CN(C)C1=C2C(N([C@H]3[C@H](O)[C@H](NC([C@@H](N)CC4=CC=C(OCC#C)C=C4)=O)[C@@H](CO)O3)C=N2)=NC=N1
• Molecular Weight: 495.53
• References & Citations: [1]Liu J, et al. Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin. Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):413-8.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported