Dynamin IN-2
CAT:
804-HY-152216-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Dynamin IN-2
- CAS Number: 1345853-49-7
- UNSPSC Description: Dynamin IN-2 (compound 43), a Wiskostatin (HY-12534) analogue, is a potent dynamin inhibitor, with an IC50 of 1.0 μM for dynamin I GTPase. Dynamin IN-2 also blocks clathrin mediated endocytosis (CME), with an IC50 of 9.5 μM[1].
- Target Antigen: Dynamin
- Type: Reference compound
- Related Pathways: Cytoskeleton
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/dynamin-in-2.html
- Solubility: 10 mM in DMSO
- Smiles: ClC(C=C1)=CC=C1CNCC(CN2C3=CC=CC=C3C4=CC=CC=C42)O
- Molecular Weight: 364.87
- References & Citations: [1]Cossar PJ, et al. Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis. Eur J Med Chem. 2022 Dec 15;247:115001.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported