Dynamin inhibitory peptide (TFA)

• UNSPSC Description:

  Dynamin inhibitory peptide TFA competitively blocks binding of dynamin to amphiphysin, thus preventing endocytosis. Dynamin inhibitory peptide TFA blocks the dopamine D3 effect on GABAA receptors[1].

• Target Antigen:

  Dynamin

• Type:

  Peptides

• Related Pathways:

  Cytoskeleton

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/dynamin-inhibitory-peptide-tfa.html

• Solubility:

  H2O

• Smiles:

  O=C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCC(N)=O)N.O=C(O)C(F)(F)F

• Molecular Weight:

  1235.27

• References & Citations:

  [1]Guojun Chen, et al. Dopamine D3 receptors regulate GABAA receptor function through a phospho-dependent endocytosis mechanism in nucleus accumbens. J Neurosci. 2006 Mar 1;26(9):2513-21.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported