Dynamin inhibitory peptide (TFA)

Dynamin inhibitory peptide (TFA)

• UNSPSC Description: Dynamin inhibitory peptide TFA competitively blocks binding of dynamin to amphiphysin, thus preventing endocytosis. Dynamin inhibitory peptide TFA blocks the dopamine D3 effect on GABAA receptors[1].
• Target Antigen: Dynamin
• Type: Peptides
• Related Pathways: Cytoskeleton
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/dynamin-inhibitory-peptide-tfa.html
• Solubility: H2O
• Smiles: O=C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCC(N)=O)N.O=C(O)C(F)(F)F
• Molecular Weight: 1235.27
• References & Citations: [1]Guojun Chen, et al. Dopamine D3 receptors regulate GABAA receptor function through a phospho-dependent endocytosis mechanism in nucleus accumbens. J Neurosci. 2006 Mar 1;26(9):2513-21.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported