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10-Nitrooleic acid

CAT: 0804-HY-101559-01Size: 50 μg (1.53 mM x 100 μL in Ethanol)Dry Ice: NoHazardous: No
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CAT#:0804-HY-101559-01Size:50 μg (1.53 mM x 100 μL in Ethanol)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
10-Nitrooleic acid (CXA-10), a nitro fatty acid, has potential effects in disease states in which oxidative stress, inflammation, fibrosis, and/or direct tissue toxicity play significant roles[1].
CAS Number
875685-46-4
Product Name Alternative
CXA-10; 10-Nitrooleate
UNSPSC
12352211
Hazard Statement
H225, H319
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/10-nitrooleic-acid.html
Concentration
1.53 mM * 200 μL in Ethanol
Purity
98.89
Solubility
10 mM in DMSO
Smiles
CCCCCCCC/C([N+]([O-])=O)=C\CCCCCCCC(O)=O
Molecular Formula
C18H33NO4
Molecular Weight
327.46
Precautions
H225, H319
References & Citations
[1]Garner RM, Mould DR, Chieffo C, Jorkasky DK. Pharmacokinetic and Pharmacodynamic Effects of Oral CXA-10, a Nitro Fatty Acid, After Single and Multiple Ascending Doses in Healthy and Obese Subjects. Clin Transl Sci. 2019;12 (6) :667-676. |[2]Zheng R, et al. Regulation of keratinocyte expression of stress proteins and antioxidants by the electrophilic nitrofatty acids 9- and 10-nitrooleic acid. Free Radic Biol Med. 2014;67:1-9.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
Phase 2

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