Products for Research Use Only
RegisterLogin

CBiPES (hydrochloride)

CAT: 0804-HY-107505-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-107505-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CBiPES hydrochloride is a mGlu2 receptor positive allosteric modulator (EC50: 92.8 nM) . CBiPES hydrochloride attenuates stress-induced hyperthermia and PCP-induced hyperlocomotor activity. CBiPES hydrochloride can be used for research of neurological disease, such as Parkinson's disease (PD) [1][2].
CAS Number
856702-40-4
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cbipes-hydrochloride.html
Purity
99.23
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CCS(N(C1=CC(C2=CC=C(C#N)C=C2)=CC=C1)CC3=CN=CC=C3)(=O)=O.[H]Cl
Molecular Formula
C21H20ClN3O2S
Molecular Weight
413.92
References & Citations
[1]Johnson MP, et al. Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model (s) . Psychopharmacology (Berl) . 2005 Apr;179 (1) :271-83.|[2]Frouni I, et al. Effect of the mGlu2 positive allosteric modulator CBiPES on dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset. J Neural Transm (Vienna) . 2021 Jan;128 (1) :73-81.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-107505A-01CBiPES
HY-B0500BAlverine (hydrochloride)
HY-W714513VU0469650 (hydrochloride)
HY-W708286-01α-Pyrrolidinobutiothiophenone (hydrochloride)
HY-W492795Quifenadine (hydrochloride)
HY-W012179-01Phenylpiperazine (hydrochloride)
HY-Z6449-01Phenylephrone (hydrochloride)
HY-W209279(±) Anabasine (hydrochloride)
HY-W027446-01Pyridoxal hydrochloride
HY-W011963-01Melevodopa (hydrochloride)

Alternative Products

CatalogName
254893-01CBiPES hydrochloride
A15811-25CBiPES hydrochloride 25mg
A15811-50CBiPES hydrochloride 50mg
A15811-10CBiPES hydrochloride 10mg
BA5555-5CBiPES
MBS3841198-01CBiPES HCl
A15811-5CBiPES HCl 5mg
A15811-1CBiPES HCl 1mg
A15811-500CBiPES HCl 500mg
A15811-100CBiPES HCl 100mg

Popular Products