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Mouse anti Lactoferrin

CAT: 0579-MUB2002PSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0579-MUB2002PSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Lactoferrin (LF), also known as lactotransferrin (LTF), is a multifunctional protein of the transferrin family. Lactoferrin is a globular glycoprotein with a molecular mass of about 80 kDa that is widely represented in various secretory fluids, such as milk, saliva, tears, and nasal secretions. Lactoferrin is also present in secondary granules of polymorphonuclear neutrophils (PMN) and is secreted by some acinar cells. The diagnosis and classifiCation of Human breast carcinomas is mainly based on morphology, which has its difficulties and limitations. Specific markers for breast tumors and additional markers, to correlate with the progress of the disease, are needed. Antibodies to Human milk-fat globule (HMFG) membranes are such potential markers for breast carcinomas. HMFG membranes carry differentiation antigens of the apical site of the secretory cell which may be present also on tumor cells.
CAS Number
9007-83-4
UniProt
P02788
Host
Mouse
Species Reactivity
Human, Mouse
Isotype
IgG2a
Clone
67D9
Type
Primary Antibodies
Source
67D9 is a Mouse monoclonal IgG2a antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with milkfat globule membranes.
Applications
IHC (frozen), IHC (paraffin), WB
Field of Research
Cancer, Cardiovascular
Assay Principle
67D2 is useful for western blot and immunohistochemistry on frozen and paraffin embedded sections. Optimal antibody dilution should be determined by titration.
Form
Each vial contains 100 µL 1 mg/mL purified monoclonal antibody in PBS containing 0,09% sodium azide
Precautions
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals. This product contains sodium azide. To prevent formation of toxic vapors, do not mix with strong acidic solutions. To prevent formation of potentially explosive metallic azides in metal plumbing, always wash into drain with copious quantities of water. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
References & Citations
1. J. Hilkens, F. Buus, J. Hegers, Ph. Hageman2, J. Calafati, A. Sonnenberg and M. Vanderval. Monoclonal Antibodies anti Human Milk-Fat Globule Membranes Detecting Differentiation Antigens Of The Mammary Gland And Its Tumors. Int J Cancer. 1984 34:197-206.
Storage Conditions
The antibody is shipped at ambient temperature and may be stored at +4°C; For prolonged storage prepare appropriate aliquots and store at or below -20°C; Prior to use, an aliquot is thawed slowly in the dark at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2); Repeated thawing and freezing should be avoided; Working dilutions should be stored at +4°C, not refrozen, and preferably used the same day; If a slight precipitation occurs upon storage, this should be removed by centrifugation; It will not affect the performance or the concentration of the product

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