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ML230

CAT: 0804-HY-111678-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-111678-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively[1].
CAS Number
[1776055-05-0]
Product Name Alternative
CID44640177; SID 88095709
UNSPSC
12352005
Target
BCRP
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ml230.html
Purity
99.65
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=C(C1=COC=C1)N2CCN(C3=CC(C4=CC=CO4)=NC5=CC(C6=CC=CC=C6)=NN53)CC2
Molecular Formula
C25H21N5O3
Molecular Weight
439.47
References & Citations
[1]Strouse JJ, et al. Selective Efflux Inhibition of ATP-binding Cassette Sub-family G Member 2. Probe Reports from the NIH Molecular Libraries Program. November 30, 2010.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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