A 410099.1

• Description:

  A 410099.1 is a BIRC inhibitor, with EC50 values for BIRC2, BIRC3, BIRC4, BIRC7, and BIRC8 are 4.6, 9.2, 15.6, 19.9, and 93.9 nM, respectively[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  IAP

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/a-410099-1.html

• Purity:

  99.30

• Solubility:

  DMSO : 50.51 mg/mL (ultrasonic; warming)

• Smiles:

  O=C([C@H]1N(CCC1)C([C@H](C2CCCCC2)NC([C@H](C)NC)=O)=O)N[C@H]3C4=CC=CC=C4CCC3.Cl

• Molecular Formula:

  C27H41ClN4O3

• Molecular Weight:

  505.09

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Schwalm MP, et al Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins. Front Cell Dev Biol. 2022 May 26;10:886537.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [762274-58-8]