Creatinase (Recombinant)
CAT:
804-HY-P2893A
Size:
500 U
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Creatinase (Recombinant)
- CAS Number: 9000-83-3
- UNSPSC Description: Creatinase (Recombinant) is a hydrolase responsible for catalyzing the hydrolysis of creatine (HY-W010388) into sarcosine (HY-101037) and urea (HY-Y0271). Creatinase (Recombinant) can be used in conjunction with creatinine deiminase (HY-P2838) and sarcosine oxidase (HY-P2861) in an enzyme cascade reaction to measure creatinine (HY-B0504) levels in blood and urine. Creatinase (Recombinant) is the rate-limiting enzyme in this enzymatic cascade, and the enzymatic quantification of creatinine is an important method for evaluating kidney function[1][2].
- Target Antigen: Endogenous Metabolite
- Type: Enzyme
- Related Pathways: Metabolic Enzyme/Protease
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/creatinase-recombinant.html
- Smiles: [Creatinase (Recombinant)]
- References & Citations: [1]Schumann J, et al. Stabilization of creatinase from Pseudomonas putida by random mutagenesis. Protein Sci. 1993 Oct;2(10):1612-20. |[2]Bai X, et al. Improved thermostability of creatinase from Alcaligenes Faecalis through non-biased phylogenetic consensus-guided mutagenesis. Microb Cell Fact. 2020 Oct 17;19(1):194.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported