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Creatinase (Recombinant)

CAT: 0804-HY-P2893A-01Size: 1 KUDry Ice: NoHazardous: No
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CAT#:0804-HY-P2893A-01Size:1 KU
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Creatinase (Recombinant) is a hydrolase responsible for catalyzing the hydrolysis of creatine into sarcosine (HY-101037) and urea (HY-Y0271). Creatinase (Recombinant) can be used in conjunction with creatinine deiminase (HY-P2838) and sarcosine oxidase (HY-P2861) in an enzyme cascade reaction to measure creatinine (HY-B0504) levels in blood and urine. Creatinase (Recombinant) is the rate-limiting enzyme in this enzymatic cascade, and the enzymatic quantification of creatinine is an important method for evaluating kidney function[1][2].
CAS Number
37340-58-2
Product Name Alternative
Creatine amidinohydrolase
UNSPSC
12352204
Target
Endogenous Metabolite
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/creatinase-recombinant.html
Smiles
[Creatinase(Recombinant)]
References & Citations
[1]Schumann J, et al. Stabilization of creatinase from Pseudomonas putida by random mutagenesis. Protein Sci. 1993 Oct;2 (10) :1612-20. |[2]Bai X, et al. Improved thermostability of creatinase from Alcaligenes Faecalis through non-biased phylogenetic consensus-guided mutagenesis. Microb Cell Fact. 2020 Oct 17;19 (1) :194.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported

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