Products for Research Use Only
RegisterLogin

DSE rabbit pAb

CAT: 0855-ES16888-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES16888-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016]
Description
The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016],
Product Name Alternative
Dermatan-sulfate epimerase (DS epimerase) (EC 5.1.3.19) (Chondroitin-glucuronate 5-epimerase) (Squamous cell carcinoma antigen recognized by T-cells 2) (SART-2)
UniProt
Q9UL01
Swiss Prot
Q9UL01
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human DSE AA range: 164-214
Target
DSE
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Molecular Weight
105kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
105kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Microsome membrane ; Multi-pass membrane protein .
Other Product Names
Dermatan-sulfate epimerase (DS epimerase) (EC 5.1.3.19) (Chondroitin-glucuronate 5-epimerase) (Squamous cell carcinoma antigen recognized by T-cells 2) (SART-2)
Gene ID (Human)
29940

Related Products

CatalogName
ES16887-01DSEL rabbit pAb
ELK9835-01Cattle DSE (Dermatan Sulfate Epimerase) ELISA Kit
ELK11370-01Chicken DSE (Dermatan Sulfate Epimerase) ELISA Kit
ELK6520-01Human DSE (Dermatan Sulfate Epimerase) ELISA Kit
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb

Alternative Products

CatalogName
RTR015Rabbit-to-Rabbit Blocking Reagent
AR05252PU-NRabbit IgG Rabbit Protein
AR05110PU-NRabbit IgM Rabbit Protein
NBP1-71681Rabbit Normal Rabbit Serum
OORA00605-100MLRabbit
KA2017Rabbit Rabbit IgG ELISA Kit
MBS9518120-01ATG4c Rabbit Rabbit Polyclonal Antibody
MBS9518118-01ATG4a Rabbit Rabbit Polyclonal Antibody
MBS9512780-01JAK2 Rabbit Rabbit Polyclonal Antibody
MBS9512768-01VEGF Rabbit Rabbit Polyclonal Antibody

Popular Products